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About Protein and Multi-Omics Lab

Proteins and Multi-Omics Lab is dedicated to exploring the intricate world of bioactive proteins, venom peptides included, shedding light on their evolution and medical significance.

Our mission is to uncover groundbreaking discoveries that contribute to the advancement of scientific knowledge and human health. Through cutting-edge research and collaboration, we strive to make a meaningful impact in the field of life sciences and medicine.

歡迎來到探索蛇毒與生物蛋白奧秘的實驗室

 

生物蛋白廣汎存在於自然界中。以神秘的蛇毒爲例,當中就含有多達上百種活性蛋白質和胜肽分子。

 

Protein and Multi-Omics實驗室的研究結合多體學(蛋白體、轉錄體、基因體)、生化及結構生物學、藥理學、免疫學和生物資訊等方式,專門探討蛋白分子在生理和病理上的機轉,並應用於新藥開發及生醫技術等領域。

 

我們實驗室的研究主題概括以下方向,歡迎有興趣的同學加入我們團隊哦!

  • 探討生物蛋白之結構與功能關係。

  • 探討生物蛋白對發炎相關病症之免疫調節功能及其抑制療法。

  • 發現生物蛋白獨特抗原性,研製臨床診斷和生物分類工具。

  • 研發抑制及中和毒性蛋白的新療法。

  • 以蛋白分子作為先導化合物, 用於藥物設計及新藥開發。

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Nature-inspired Protein Research

Snake venoms contain various bioactive proteins and peptides. With their potent bioactive properties, we have been long intrigued for their potential applications in various fields such as medicine, agriculture, and biotechnology. Incorporating approaches of multi-omics (proteomics, transcriptomics, genomics), molecular and structural biology, pharmacology, immunology, and bioinformatics etc., these proteins and peptides can be used to elucidate physiological and pathological mechanisms, and harnessed in drug discovery as well as biomedical technologies. Our laboratory has a clear research vision covering the following directions, and we warmly welcome interested students to join us.

  •  Investigating the structures and functions of bioactive proteins.

  •  Investigating the immuno-modulatory functions of bioactive proteins in inflammatory conditions and the therapeutic approach.

  •  Exploring unique antigenicity of proteins for the development of disease diagnostics and molecular markers in taxonomy.

  •  Development of novel treatments that inhibit and neutralize toxicity associated with bioactive proteins.

  •  Drug design and drug discovery inspired by bioactive proteins as drug leads. 

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