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Research Publications

Publications：

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  1. Lim, A.S.S., Tan, K.Y., Tan, C.H.*. Immunoreactivity and neutralization efficacy of Pakistani Viper Antivenom (PVAV) against venoms of Saw-scaled Vipers (Echis carinatus subspp.) and Western Russell's Vipers (Daboia russelii) from the Indian subcontinent. Acta Trop. 2024, 250:107099. doi: 10.1016/j.actatropica.2023.107099. (SCIE, IF: 3.222, Tier 1, Corresponding author*)
    2.      Tan, C.H.*, Tan, K.Y., Ng, T.S., Tan, N.H., Chong, H.P. De Novo Venom Gland Transcriptome Assembly and Characterization for Calloselasma rhodostoma (Kuhl, 1824), the Malayan Pit Viper from Malaysia: Unravelling Toxin Gene Diversity in a Medically Important Basal Crotaline. Toxins 2023, 15, 315. (SCIE, IF: 5.075, Tier 1, Corresponding author*)
    3.      Tan, C.H.*; Tan, K.Y.; Tan, N.H. De Novo Assembly of Venom Gland Transcriptome of Tropidolaemus wagleri (Temple Pit Viper, Malaysia) and Insights into the Origin of Its Major Toxin, Waglerin. Toxins 2023, 15, 585. (SCIE, IF: 5.075, Tier 1, Corresponding author*)
    4.      Lim, A.S.S., Tan, K.Y., Quraishi, N.H., Farooque, S., Khoso, Z.A., Ratanabanangkoon, K. Tan, C.H.* 2023. Proteomic analysis, immuno-specificity and neutralization efficacy of Pakistani Viper Antivenom (PVAV), a bivalent anti-Viperid antivenom produced in Pakistan. Toxins, 15, 265. (SCIE, IF: 5.075, Tier 1, Corresponding author*)
    5.      Lee, L.P., Tan, CH.*, Khomvilai, S., Sitprija, V., Chaiyabutr, N., Tan, K.Y. 2023. Characterizing and applying immunoglobulins in snakebite diagnostics: A simple and rapid venom detection assay for four medically important snake species in Southeast Asia. International Journal of Biological Macromolecules, 236, 123727, doi.org/10.1016/j.ijbiomac.2023.123727. (SCIE, IF: 8.025, Tier 1, Corresponding author*)
    6.      Blessmann, J., Hanlodsomphou, S., Santisouk, B., Krumkamp, R., Kreuels, B., Ismail, A.K., Yong, M.Y., Tan, K.Y., Tan, C.H. (2023) Experience of using expired lyophilized snake antivenom during a medical emergency situation in Lao People's Democratic Republic--A possible untapped resource to tackle antivenom shortage in Southeast Asia. Trop Med Int Health, 28, 64-70. (SCIE, IF: 3.918, Tier 1)
    7.      Palasuberniam, P., Tan, K. Y., Chan, Y. W., Blanco, F. B., & Tan, C. H.* (2023). Decomplexation proteomic analysis and purity assessment of a biologic for snakebite envenoming: Philippine Cobra Antivenom. Transactions of the Royal Society of Tropical Medicine and Hygiene, 117(6), 428–434. https://doi.org/10.1093/trstmh/trac125. (SCIE, IF: 2.820, Tier 3, Corresponding author*)
    8.      Tan, C.H.*, Wong, K.Y., Huang, L.-K., Tan, K.Y., Tan, N.H.; Wu, W.-G. (2022) Snake Venomics and Antivenomics of Cape Cobra (Naja nivea) from South Africa: Insights into Venom Toxicity and Cross-Neutralization Activity. Toxins, 14, 860. (SCIE, IF: 5.075, Tier 1, First and corresponding author*)
    9.      Tan, C.H.*, Oh, A.M.F., Wong, K.Y., Liew, J.L., Tan, N.H., Tan, K.Y. (2022) On characterizing the Red-headed Krait (Bungarus flaviceps) venom: Decomplexation proteomics, immunoreactivity and toxicity cross-neutralization by hetero-specific antivenoms. Comp Biochem Physiol Part D Genomics Proteomics, 43, 101006. (SCIE, IF: 3.306, Tier 2, First and corresponding author*)
    10.    Stazi, M., Fabris, F., Tan, K.Y., Megighian, A., Rubini, A., Mattarei, A., Negro, S., D'Este, G., Lista, F., Rossetto, O., Tan, C.H.*, Montecucco, C. (2022) An agonist of the CXCR4 receptor is therapeutic for the neuroparalysis induced by Bungarus snakes envenoming.  Clinal Translational Medicine. 12, e651. (SCIE, IF: 11.49, Tier 1, Corresponding author*)
    11.    Tan, C.H*., Tan, K.Y., Wong, K.Y., Tan, N.H., Chong, H.P. (2022). Equatorial Spitting Cobra (Naja sumatrana) from Malaysia (Negeri Sembilan and Penang), Southern Thailand, and Sumatra: Comparative Venom Proteomics, Immunoreactivity and Cross-Neutralization by Antivenom. Toxins, 14(8), 522. (SCIE, IF: 5.075, Tier 1, First and corresponding author*)
    12.    Tan, C.H.* (2022) Snake Venomics: Fundamentals, Recent Updates, and a Look to the Next Decade. Toxins, 14, 247. (SCIE, IF: 5.075, Tier 1, First and corresponding author*)
    13.    Ong, H.L., Tan, C.H., Lee, L.P., Khor, S.M., Tan, K.Y. (2022) An immunodetection assay developed using cobra cytotoxin-specific antibodies: Potential diagnostics for cobra envenoming. Toxicon.  16, 157–168. doi:10.1016/j.toxicon.2022.07.010 (SCIE, IF: 3.033, Tier 3)
    14.    Chong, H.P., Tan, K.Y., Liu, B-S., Sung, W-C., Tan, C.H.* (2022) Cytotoxicity of Venoms and Cytotoxins from Asiatic Cobras (Naja kaouthia, Naja sumatrana, Naja atra) and Neutralization by Antivenoms from Thailand, Vietnam, and Taiwan. Toxins. 2022; 14(5):334. (SCIE, IF: 5.075, Tier 1, corresponding author*)
    15.    Tan, K.Y., Shamsuddin, N.N.B., Tan, C.H.* (2022) Sharp-nosed Pit Viper (Deinagkistrodon acutus) from Taiwan and China: A comparative study on venom toxicity and neutralization by two specific antivenoms across the Strait. Acta Tropica, 232, 106495. (SCI, IF: 3.222, Tier 1, Corresponding author*)
    16.    Tan, C.H.*, Tan, K.Y., Jackson, T.N.W. (2022) Editorial: Venoms and Toxins: Functional Omics and Pharmacological Insights. Frontiers in Pharmacology 13, 887513. (SCIE, IF: 5.988, Tier 1, Corresponding author*)
    17.    Tan, C.H.*; Bourges, A.; Tan, K.Y. (2022) King Cobra and snakebite envenomation: On the natural history, human-snake relationships and medical importance of Ophiophagus hannah. Journal of Venomous Animals and Toxins including Tropical Diseases, 27: e20210051. (SCI, IF: 2.45, Tier 2, First and corresponding author*)
    18.    Chan, Y.W., Tan, K.Y., Tan, C.H.* (2022) Preclinical assessment of VPEAV, a new trivalent antivenom for elapid snakebite envenoming in the Philippines: Proteomics, immunoreactivity and toxicity neutralization. Toxicon. 220:106942. (SCIE, IF: 3.033, Tier 3, Corresponding author*)
    19.    Tan, C.H.*, Lingam, T.M.C., Tan, K.Y. (2022) Varespladib (LY315920) rescued mice from fatal neurotoxicity caused by venoms of five major Asiatic kraits (Bungarus spp.) in an experimental envenoming and rescue model. Acta Tropica 227, 106289. (SCI, IF: 3.222, Tier 1, First and corresponding author*)
    20.    Dashevsky, D., Deuis, J.R., Vetter, I., Huynh, T., Hodgson, W.C., Tan, C.H., Nouwens, A., Fry, B.G. (2022) Novel Neurotoxic Activity in Calliophis intestinalis Venom. Neurotoxicity Research 40, 173-178. (SCI, IF: 3.54, Tier 2)
    21.    Choo, S.W., Chong, J.L., Gaubert, P., Hughes, A.C., O'Brien, S., .........Tan, C.H., Xu, H., Paterson, I.C., Wang, M., Chan, C.K., Zhang, S., Dutta, A., Tee, T.S., Juvigny-Khenafou, N.P.D., Mutha, N.V.R., Aziz, M.A. (2022) A collective statement in support of saving pangolins. The Science of the Total Environment 824, 153666. (SCI, IF: 7.963, Tier 1)
    22.    Palasuberniam, P., Chan, Y.W., Tan, K.Y., Tan, C.H.* (2021) Snake Venom Proteomics of Samar Cobra (Naja samarensis) from the Southern Philippines: Short Alpha-Neurotoxins as the Dominant Lethal Component Weakly Cross-Neutralized by the Philippine Cobra Antivenom. Frontiers in Pharmacology, 12, 727756. (SCI, IF: 5.988, Tier 1, Corresponding author*)
    23.    Lingam, T.M.C., Tan, K.Y., Tan, C.H.* (2021) Capillary leak syndrome induced by the venoms of Russell's Vipers (Daboia russelii and Daboia siamensis) from eight locales and neutralization of the differential toxicity by three snake antivenoms. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 250, 109186. (SCI, IF: 3.22, Tier 1, Corresponding author*)
    24.    Yong, M.Y., Tan, K.Y., Tan, C.H.* (2021) Potential para-specific and geographical utility of Thai Green Pit Viper (Trimeresurus albolabris) Monovalent Antivenom: Neutralization of procoagulant and hemorrhagic activities of diverse Trimeresurus pit viper venoms. Toxicon 203, 85-92. (SCIE, IF: 3.033, Tier 3, Corresponding author*)
    25.    Wong, K.Y., Tan, K.Y., Tan, N.H., Gnanathasan, C.A., Tan, C.H.* (2021) Elucidating the Venom Diversity in Sri Lankan Spectacled Cobra (Naja naja) through De Novo Venom Gland Transcriptomics, Venom Proteomics and Toxicity Neutralization. Toxins 13, 558. (SCIE, IF: 5.075, Tier 1, corresponding author*)
    26.    Lee, L.P.; Tan, K.Y.; Tan, C.H.* (2021) Snake venom proteomics and antivenomics of two Sundaic lance-headed pit vipers: Trimeresurus wiroti (Malaysia) and Trimeresurus puniceus (Indonesia). Comp Biochem Physiol D Genomics Proteomics, 40: 100875. (*corresponding author) (SCI, ISI-indexed) (SCI, IF: 3.306, Tier 1, Corresponding author*)
    27.    Oh, A.M.Y.; Tan, K.Y., Tan, N.H., Tan, C.H.* (2021) Proteomics and neutralization of Bungarus multicinctus (Many-banded Krait) venom: Intra-specific comparisons between specimens from China and Taiwan. Comp Biochem Physiol C Toxicol Pharmacol. 247, 109063. (SCIE, IF: 4.159, Tier 1, Corresponding author*)
    28.    Palasuberniam, P.; Tan, K.Y.; Tan, C.H.* (2021) De novo venom gland transcriptomics of Calliophis bivirgata flaviceps: Uncovering the complexity of toxins from Malayan Blue Coral Snake. Journal of Venomous Animals and Toxins including Tropical Diseases, 27, e20210024. (SCI, IF: 2.474, Tier 2, Corresponding author*)
    29.    Faisal, T., Tan, K.Y., Tan, N.H., Sim, S.M., Gnanathasan, C.A., Tan, C.H.* (2021) Proteomics, toxicity and antivenom neutralization of Sri Lankan and Indian Russell’s viper (Daboia russelii) venoms. Journal of Venomous Animals and Toxins including Tropical Diseases, 27, e20200177. (SCI, IF: 2.474, Tier 2, Corresponding author*)
    30.    Tan, C.H.*; Tan, K.Y. (2021) De Novo Venom-Gland Transcriptomics of Spine-Bellied Sea Snake (Hydrophis curtus) from Penang, Malaysia— Next-Generation Sequencing, Functional Annotation and Toxinological Correlation. Toxins, 13, 127. (SCIE, IF: 5.075, Tier 1, First and corresponding author*)
    31.    Tan, C.H.*; Palasuberniam, P.; Blanco F.B.; Tan, K.Y. (2021) Immunoreactivity and neutralization capacity of Philippine Cobra Antivenom (PCAV) against the venoms of Naja philippinensis and Naja samarensis. Transactions of the Royal Society of Tropical Medicine & Hygiene, 115, 78-84. (SCI, IF: 2.820, Tier 3, Corresponding author*)
    32.    Wong, K.Y.; Tan, K.Y.; Tan, N.H.; Tan, C.H.* (2021) A Neurotoxic Snake Venom without Phospholipase A2: Proteomics and Cross-Neutralization of the Venom from Senegalese Cobra, Naja senegalensis (Subgenus: Uraeus). Toxins, 13, 60. (SCIE, IF: 5.075, Tier 1, corresponding author*)
    33.    Tan, C.H.*, Liew, J.L., Chong, H.P., Tan, N.H. (2021) Protein decomplexation and proteomics: A complementary assessment method of the physicochemical purity of antivenom. Biologicals, 69, 22-29. (SCI, IF: 1.809, Tier 4, First and corresponding author*)
    34.    Tan, N.H., Tan, K.Y., Tan, C.H.* (2021) Snakebite in Southeast Asia: Envenomation and Clinical Management., in: Mackessy, S.P. (Ed.), Handbook of Venoms and Toxins of Reptiles, 2nd ed. CRC Press, Boca Raton, USA, pp. 559-579. (Book chapter, *corresponding author)
    35.    Tan, K.Y., Wong, K.Y., Tan, N.H., Tan, C.H.* (2020) Quantitative proteomics of Naja annulifera (sub-Saharan snouted cobra) venom and neutralization activities of two antivenoms in Africa. Int J Biol Macromol., 158, 605-616. doi: 10.1016/j.ijbiomac.2020.04.173. (SCIE, IF: 8.025, Tier 1, Corresponding author*)
    36.    Tan, C.H.*, Liew, J.L., Navanesan, S., Sim. K.S., Tan, N.H., Tan, K.Y. (2020) Cytotoxic and anticancer properties of the Malaysian mangrove pit viper (Trimeresurus purpureomaculatus) venom and its disintegrin (purpureomaculin). Journal of Venomous Animals and Toxins including Tropical Diseases, 26, e20200013. (SCI, IF: 2.474, Tier 2, First and corresponding author*)
    37.    Pruksaphon, K., Tan, K.Y., Tan, C.H., Simsiriwong, P., Gutiérrez, J.M., Ratanabanangkoon, K. (2020). An in vitro α-neurotoxin AChR binding assay correlates with lethality and in vivo neutralization of a large number of elapid neurotoxic snake venoms from four continents. PLOS Neglected Tropical Disease, 14(8): e0008581. (SCIE, IF: 4.521, Tier 1)
    38.    Ratanabanangkoon, K., Tan, K.Y., Pruksaphon, K., Klinpayom, C., Gutierrez, J.M., Quraishi, N.H., Tan, C.H.* (2020) A pan-specific antiserum produced by a novel immunization strategy shows a high spectrum of neutralization against neurotoxic snake venoms. Scientific Reports, 10, 11261. (SCIE, IF: 4.996, Tier 1, Corresponding author*)
    39.    Chong, H.P., Tan, K.Y., Tan, C.H.* (2020) Cytotoxicity of Snake Venoms and Cytotoxins from Two Southeast Asian Cobras (Naja sumatrana, Naja kaouthia): Exploration of Anticancer Potential, Selectivity, and Cell Death Mechanism. Front. Mol. Biosci. 7:583587. doi: 10.3389/fmolb.2020.583587. (SCI, IF: 6.113, Tier 1, Corresponding author)
    40.    Liew, J.L., Tan, N.H., Tan, C.H.* (2020) Proteomics and preclinical antivenom neutralization of the mangrove pit viper (Trimeresurus purpureomaculatus, Malaysia) and white-lipped pit viper (Trimeresurus albolabris, Thailand) venoms. Acta Tropica, 209, 105528. doi: 10.1016/j.actatropica.2020.105528. (SCI, IF: 3.10, Tier 1, Corresponding author*)
    41.    Lee, L.P., Tan, K.Y., Tan, C.H.* (2020) Toxicity and cross-neutralization of snake venoms from two lesser-known arboreal pit vipers in Southeast Asia: Trimeresurus wiroti and Trimeresurus puniceus. Toxicon, 185, 91–96. (SCIE, IF: 3.033, Tier 3, Corresponding author*)
    42.    Hia, Y.L., Tan, K.Y., Tan, C.H.* (2020) Comparative venom proteomics of banded krait (Bungarus fasciatus) from five geographical locales: Correlation of venom lethality, immunoreactivity and antivenom neutralization. Acta Tropica, 207, 105460. doi: 10.1016/j.actatropica.2020.105460. (SCI, IF: 3.222, Tier 1, Corresponding author*)
    43.    Tan, K.Y., Ng, T.S., Bourges, A., Ismail, A.K., Maharani, T., Khomvilai, S., Sitprija, V., Tan, N.H., Tan, C.H.* (2020) Geographical variations in king cobra (Ophiophagus hannah) venom from Thailand, Malaysia, Indonesia and China: On venom lethality, antivenom immunoreactivity and in vivo neutralization. Acta Tropica, 203, 105311. (SCI, IF: 3.10, Tier 1, Corresponding author*)
    44.    Lingam, T.M.C., Tan, K.Y., Tan, C.H.* (2020) Proteomics and antivenom immunoprofiling of Russell’s viper (Daboia siamensis) venoms from Thailand and Indonesia. Journal of Venomous Animals and Toxins including Tropical Diseases, 26, e20190048. Doi:10.1590/1678-9199-jvatitd-2019-0048. (SCI, IF: 2.474, Tier 2, First and corresponding author*)
    45.    Sim, D.S.M., Tan, C.H., Amir, A. (2020) To change or not to change- Moving from traditional teaching to problem-based learning (PBL) at University Malaya medical school. In Shahbodin, F, & Jano, Z., Problem Based Learning Best Practices, Research and Development (pp. 93-104). University Press, Universiti Teknikal Malaysia Melaka. (Book chapter)
    46.    Tan, C.H.*, Tan, K.Y., Ng, T.S., Sim, S.M., Tan, N.H. (2019) Venom Proteome of Spine-Bellied Sea Snake (Hydrophis curtus) from Penang, Malaysia: Toxicity Correlation, Immunoprofiling and Cross-Neutralization by Sea Snake Antivenom. Toxins, 11(1), 3, doi:10.3390/toxins11010003. (SCIE, IF: 5.075, Tier 1, First and corresponding author*)
    47.    Tan, C.H.*, Wong, K.Y., Chong, H.P., Tan, N.H., Tan, K.Y. (2019) Proteomic insights into short neurotoxin-driven, highly neurotoxic venom of Philippine cobra (Naja philippinensis) and toxicity correlation of cobra envenomation in Asia. Journal of Proteomics, 206, 103418. (SCI, IF: 3.855, Tier 2, First and corresponding author*)   
    48.    Tan, K.Y.; Liew, S.T.; Tan, Q.Y.; Abdul-Rahman, F.N.; Azmi, N.I.; Sim, S.M.; Tan, N.H.; Khomvilai, S.; Sitprija, V.; Tan, C.H.* (2019) Evaluating the physicochemical properties and efficacy of recently expired and aged antivenom products from Thailand and Taiwan. Toxicon, 160, 55–58. doi: 10.1016/j.toxicon.2019.02.010. (SCIE, IF: 3.033, Tier 3, Corresponding author*)
    49.    Tan, K.Y.; Liew, J.L.; Tan, N.H.; Quah, E.S.H.; Ismail, A.K.; Tan, C.H.* (2019) Unlocking the secrets of banded coral snake (Calliophis intestinalis, Malaysia): A venom with proteome novelty, low toxicity and distinct antigenicity. J Proteomics 2019, 192, 246-257, doi:10.1016/j.jprot.2018.09.006. (SCI, IF: 4.044, Tier 2, First and corresponding author*)   
    50.    Tan, C.H.; Wong, K.Y.; Tan, N.H.; Ng, T.S.; Tan, K.Y. (2019) Distinctive distribution of secretory phospholipases A2 in the venoms of Afro-Asian cobras (subgenus: Naja, Afronaja, Boulengerina and Uraeus. Toxins (Basel), 11(2), 116, doi:10.3390/toxins11020116. (SCIE, IF: 5.075, Tier 1, First author*)
    51.    Tan, C.H.*; Tan, K.Y.; Ng, T.S.; Quah, E.S.H.; Ismail, A.K.; Khomvilai, S.; Sitprija, V.; Tan, N.H. (2019) Venomics of Trimeresurus (Popeia) nebularis, the Cameron Highlands pit viper from Malaysia: Insights into venom proteome, toxicity and neutralization of antivenom. Toxins, 11(2), 95. (SCIE, IF: 5.075, Tier 1, First and corresponding author*)
    52.    Tan, C.H.*; Tan, K.Y. (2019) Functional Application of Snake Venom Proteomics in In Vivo Antivenom Assessment. In Functional Proteomics: Methods and Protocols, Wang, X., Kuruc, M., Eds. Humana Press, New York, USA, 1871, pp. 153-158. doi:10.1007/978-1-4939-8814-3_11 (Book chapter, *First and corresponding author)
    53.    Chong, H.P.; Tan, K.Y.; Tan, N.H.; Tan, C.H.* (2019) Exploring the Diversity and Novelty of Toxin Genes in Naja sumatrana, the Equatorial Spitting Cobra from Malaysia through De Novo Venom-Gland Transcriptomics. Toxins, 11(2), 104, doi:10.3390/toxins11020104. (SCI, IF: 5.075, Tier 1, Corresponding author*)
    54.    Tan, C.H.*; Tan, K.Y.; Tan, N.H. (2019) A Protein Decomplexation Strategy in Snake Venom Proteomics. In Functional Proteomics: Methods and Protocols, Wang, X., Kuruc, M., Eds. Humana Press, New York, USA, 1871, 83-92. doi: 10.1007/978-1-4939-8814-3_5 (SCI, IF: 1.17, Tier 4, First and corresponding author*)
    55.    Tan, C.H.*; Tan, K.Y.; Wong, K.Y.; Oh, A.M.F.; Faisal, T.; Sim, S.M.; Tan, N.H. (2019) Mapping snake venomics: Insights into biomedical and evolutionary significance of snake toxins. Toxicon 158, S10-S11, doi:10.1016/j.toxicon.2018.10.043. (SCIE, IF: 3.033, Tier 3, First and corresponding author*)
    56.    Tan, K.Y.; Tan, C.H.*; Sim, S.M.; Khomvilai, S.; Sitprija, V.; Tan, N.H. (2019) Appreciating expired snake antivenoms: a plausible alternative solution to overcome antivenom shortage. Toxicon, 158, S32, doi:10.1016/j.toxicon.2018.10.113. (SCI, IF: 3.033, Tier 3, Corresponding author*)
    57.    Wong, K.Y., Tan, C.H.*, Tan, K.Y., Tan, N.H. (2019) Exploring the efficacy and limitation of antivenom neutralization against key venom toxins of Afro-Asian cobras (Naja spp.). Toxicon, 158, S45-S46, doi:10.1016/j.toxicon.2018.10.160. (SCI, IF: 3.033, Tier 3, Corresponding author*)
    58.    Chaisakul, J., Alsolaiss, J., Charoenpitakchai, M., Wiwatwarayos, K., Sookprasert, N., Harrison, R.A., Chaiyabutr, N., Chanhome, L., Tan, C.H., Casewell, N.R. (2019) Evaluation of the geographical utility of Eastern Russell's viper (Daboia siamensis) antivenom from Thailand and an assessment of its protective effects against venom-induced nephrotoxicity. PLOS Neglected Tropical Diseases 13(10), e0007338. (SCIE, IF: 4.521, Tier 1)
    59.    Chua, S.S., Lai, P.S.M., Sim, S.M., Tan, C.H., Foong, C.C. (2019) Acceptance of interprofessional learning between medical and pharmacy students in a prescribing skills training workshop: Pre-post intervention study. BMC Medical Education, 19: 101. (SCI, IF: 2.37, Tier 2)
    60.    Tang, E.L.H., Tan, N.H., Fung, S.Y., Tan, C.H.* (2019) Comparative proteomes, immunoreactivities and neutralization of procoagulant activities of Calloselasma rhodostoma (Malayan pit viper) venoms from four regions in Southeast Asia. Toxicon. 169:91–102. doi:10.1016/j.toxicon.2019.08.004. (SCI, IF: 3.033, Tier 3, Corresponding author*)
    61.    Wong, K.Y., Tan, C.H.*; Tan, K.Y., Quraishi, N.H., Tan, N.H. (2018) Elucidating the biogeographical variation of the venom of Naja naja (spectacled cobra) from Pakistan through a venom-decomplexing proteomic study. J Proteomics, 175, 156-173, doi:10.1016/j.jprot.2017.12.012. (SCIE, IF: 4.044, Tier 2, Corresponding author*)   
    62.    Ratanabanangkoon, K.; Simsiriwong, P.; Pruksaphon, K.; Tan, K.Y.; Chantrathonkul, B.; Eursakun, S.; Tan, C.H.* (2018) An in vitro potency assay using nicotinic acetylcholine receptor binding works well with antivenoms against Bungarus candidus and Naja naja. Scientific Reports, 8, 9716, doi:10.1038/s41598-018-27794-3. (SCIE, IF: 4.996, Tier 1, Corresponding author*)
    63.    Oh, A.M.F.; Tan, C.H.*; Tan, K.Y.; Quraishi, N.H.; Tan, N.H. (2018) Venom proteome of Bungarus sindanus (Sind krait) from Pakistan and in vivo cross-neutralization of toxicity using an Indian polyvalent antivenom. J Proteomics, 10.1016/j.jprot.2018.10.016, doi:10.1016/j.jprot.2018.10.016. (SCIE, IF: 4.044, Tier 2, Corresponding author*)
    64.    Faisal, T.; Tan, K.Y.; Sim, S.M.; Quraishi, N.; Tan, N.H.; Tan, C.H.* (2018) Proteomics, functional characterization and antivenom neutralization of the venom of Pakistani Russell's viper (Daboia russelii) from the wild. J Proteomics, 183, 1-13, doi:10.1016/j.jprot.2018.05.003. (SCIE, IF: 4.044, Tier 2, Corresponding author*)
    65.    Tan, K.Y.; Tan, N.H.; Tan, C.H.* (2018) Venom proteomics and antivenom neutralization for the Chinese eastern Russell's viper, Daboia siamensis from Guangxi and Taiwan. Scientific Reports 2018, 8, 8545, doi:10.1038/s41598-018-25955-y. (SCI, IF: 4.379, Tier 1, Corresponding author*)
    66.    Tan, C.H., Amir, A. (2018) Enhancing student learning through problem-based learning. In: Sim, J.H., Foong, C.C., Hong, W.H., Pallath, V., & Vadivelu, J. (Eds.). Enhancing student learning in medical schools. Kuala Lumpur, Malaysia: University of Malaya Press. (Book chapter)
    67.    Tan, C.H.*, Liew, J.L., Tan, N.H., Ismail, A.K., Maharani, T., Khomvilai, S., Sitprija, V. (2017) Cross reactivity and lethality neutralization of venoms of Indonesian Trimeresurus complex species by Thai Green Pit Viper Antivenom. Toxicon, 140:32-37. doi: 10.1016/j.toxicon.2017.10.014. (SCIE, IF: 3.033, Tier 3, First and corresponding author*)
    68.    Tan, C.H.*, Tan, K.Y., Yap, M.K., Tan, N.H. (2017) Venomics of Tropidolaemus wagleri, the sexually dimorphic temple pit viper: Unveiling a deeply conserved atypical toxin arsenal. Scientific Reports. 7:43237. (SCIE, IF: 4.996, Tier 1, First and corresponding author*)
    69.    Tan, N.H., Wong, K.Y., Tan, C.H.*. (2017) Venomics of Naja sputatrix, the Javan spitting cobra: A short neurotoxin-driven venom needing improved antivenom neutralization. J Proteomics. 157:18-32. (SCI, IF: 4.044, Tier 2, Corresponding author*)
    70.    Tan, K.Y., Tan, C.H.*, Chanhome L, Tan NH. (2017) Comparative venom gland transcriptomics of Naja kaouthia (monocled cobra) from Malaysia and Thailand: elucidating geographical venom variation and insights into sequence novelty. PeerJ. 5:e3142. (SCI, IF: 2.98, Tier 1, Corresponding author*)
    71.    Tan, C.H.*, Wong, K.Y., Tan, K.Y., Tan, N.H. (2017) Venom proteome of the yellow-lipped sea krait, Laticauda colubrina from Bali: Insights into subvenomic diversity, venom antigenicity and cross-neutralization by antivenom. J Proteomics. 166:48-58. (SCI, IF: 4.044, Tier 2, First and corresponding author*)
    72.    Oh, A.M.F., Tan, C.H.*, Gnanathasan, C.A., Naeem, Q., Tan, N.H. (2017) Venomics of Bungarus caeruleus (Indian krait): Comparable venom profiles, variable immunoreactivities among specimens from Sri Lanka, India and Pakistan. J Proteomics. 163:1-18. (SCI, IF: 4.044, Tier 2, Corresponding author*)
    73.    Ratanabanangkoon, K., Simsiriwong, P., Pruksaphon, K., Tan, K.Y., Eursakun, S., Tan, C.H., Chantrathonkul, B., Wongwadhunyoo, W., Youngchim, S., Tan, N.H. (2017) A novel in vitro potency assay of antisera against Thai Naja kaouthia based on nicotinic acetylcholine receptor binding. Scientific Reports. 7(1):8545. doi: 10.1038/s41598, (SCI, IF: 4.379, Tier 1)
    74.    Tan, C.H.*, Tan, N.H. (2017) Toxinology of snake venoms: The Malaysian context. Gopalakrishnakone P, Inagaki H, Mukherjee AK, Rahmy TR, Vogel C-W, eds. Snake Venoms. Springer Netherlands, 1-37. (Book chapter, First author*)
    75.    Tan, C.H.*, Liew, J.L., Tan, K.Y., Tan, N.H. (2016) Assessing SABU (Serum Anti Bisa Ular), the sole Indonesian antivenom: A proteomic analysis and neutralization efficacy study. Sci Rep. 6:37299. doi:10.1038/srep37299. (SCI, IF: 4.379, Tier 1, First and corresponding author)
    76.    Tan, C.H.*, Tan, K.Y., Tan, N.H. (2016) Revisiting Notechis scutatus venom: on shotgun proteomics and neutralization by the "bivalent" Sea Snake Antivenom. J Proteomics 144: 33-38. (SCI, IF: 4.044, Tier 2, First and corresponding author*)
    77.    Tan, C.H.*, Fung, S.Y., Yap, M.K., Leong, P.K., Liew, J.L., Tan, N.H. (2016) Unveiling the elusive and exotic: Venomics of the Malayan blue coral snake (Calliophis bivirgata flaviceps). J Proteomics 132:1-12. (SCI, IF: 4.044, Tier 2, First and corresponding author*)
    78.    Wong, K.Y., Tan, C.H.*, Tan, N.H. (2016) Venom and purified toxins of the spectacled cobra (Naja naja) from Pakistan: Insights into toxicity and antivenom neutralization. Am J Trop Med Hyg. 94(6):1392-1399 (SCI, IF: 2.345, Tier 1, Corresponding author*)
    79.    Tang, E.L., Tan, C.H.*, Fung, S.Y., Tan, N.H. (2016) Venomics of Calloselasma rhodostoma, the Malayan pit viper: A complex toxin arsenal unraveled. J Proteomics 148:44-56. (SCI, IF: 4.044, Tier 2, Corresponding author*)
    80.    Tan, C.H.*, Liew, J.L., Tan, K.Y., Tan, N.H. (2016) Genus Calliophis of Asiatic coral snakes: A deficiency of venom cross-reactivity and neutralization against seven regional elapid antivenoms. Toxicon 121, 130-133. (SCI, IF: 2.73, Tier 3, First and corresponding author*)
    81.    Tan, N.H., Tan, C.H. (2016) Cytotoxicity of snake venoms and toxins: Mechanisms and applications. In Y. N. Utkin & A. V. Krivoshein (Eds.), Snake Venoms and Envenomation. Modern Trends and Future Prospects (pp. 303). New York, USA: Nova Science Publishers. (Book chapter)
    82.    Tan, K.Y., Tan, C.H.*, Sim, S.M., Fung, S.Y., Tan, N.H. (2016) Geographical venom variations of the Southeast Asian Monocled Cobra (Naja kaouthia): Venom-induced neuromuscular depression and antivenom neutralization. Comp Biochem Physiol C Toxicol Pharmacol. 185-186, 77-86. (SCIE, IF: 4.159, Tier 1, Corresponding author*)
    83.    Tan, K.Y., Tan, C.H.*, Fung, S.Y., Tan, N.H. (2016) Neutralization of the principal toxins from the venoms of Thai Naja kaouthia and Malaysian Hydrophis schistosus: Insights into toxin-specific neutralization by two different antivenoms. Toxins, 8, 86. (SCI, IF: 5.075, Tier 1, Corresponding author*)
    84.    Ratanabanangkoon, K., Tan, K.Y., Eursakun, S., Tan, C.H., Simsiriwong, P., Pamornsakda, T., Wiriyarat, W., Klinpayom, C., Tan, N.H. (2016) A simple and novel strategy for the production of a pan-specific antiserum against elapid snakes of Asia. PLoS Negl Trop Dis. 10, e0004565. (SCIE, Tier 1, IF: 4.521)
    85.    Tan, C.H.*, Tan, N.H., Tan, K.Y., Kwong, K.O. (2015) Antivenom cross-neutralization of the venoms of Hydrophis schistosus and Hydrophis curtus, two common sea snakes in Malaysian waters. Toxins (Basel) 7, 572-81. (SCI, IF: 5.075, Tier 1, First and corresponding author*)
    86.    Tan, C.H.*, Tan, N.H., Sim, S.M., Fung, S.Y., Gnanathasan, C.A. (2015) Proteomic investigation of Sri Lankan hump-nosed pit viper (Hypnale hypnale) venom. Toxicon 93:164-70. (SCI, IF: 2.73, Tier 3, First and corresponding author*)
    87.    Tan, C.H.*, Tan, K.Y., Lim, S.E., Tan, N.H. (2015) Venomics of the beaked sea snake, Hydrophis schistosus: A minimalist toxin arsenal and its cross-neutralization by heterologous antivenoms. J Proteomics 126, 121-130. (SCI, IF: 4.044, Tier 2, First and corresponding author*)
    88.    Tan, C.H.*, Tan, K.Y., Fung, S.Y., Tan, N.H. (2015)  Venom-gland transcriptome and venom proteome of the Malaysian king cobra (Ophiophagus hannah). BMC Genomics. 16, 687. (SCI, IF: 3.82, Tier 1, First and corresponding author*)
    89.    Tan, N.H., Fung, S.Y., Tan, K.Y., Yap, M.K., Gnanathasan, C.A., Tan, C.H.* (2015) Functional venomics of the Sri Lankan Russell's viper (Daboia russelii) and its toxinological correlations. J Proteomics 128, 403-423. (SCI, IF: 4.044, Tier 2, Corresponding author*)
    90.    Tan, K.Y., Tan, C.H.*, Fung, S.Y., Tan, N.H. (2015) Venomics, lethality and neutralization of Naja kaouthia (monocled cobra) venoms from three different geographical regions of Southeast Asia. J Proteomics 120: 105-125. (SCI, IF: 4.044, Tier 2, Corresponding author*)
    91.    Tan, C.H.*, Ismail, A.K. (2015) The poisoned patient. Chan KY, Ng PK, Sim MDS, eds. Pharmacological Basis of Acute Care. Cham: Springer International Publishing, 219-225. (Book chapter, Corresponding author*)
    92.    Tan, C.H.* (2015)  Dose response relationship. Chan KY, Ng PK, Sim MDS, eds. Pharmacological Basis of Acute Care. Cham: Springer International Publishing, 57-64. (Book chapter, corresponding author*)
    93.    Yap, M.K., Tan, N.H., Sim, S.M., Fung, S.Y., Tan, C.H. (2015) The effect of a polyvalent antivenom on the serum venom antigen levels of Naja sputatrix (Javan spitting cobra) venom in experimentally envenomed rabbits. Basic Clin Pharmacol Toxicol 117: 274-279. (SCI, Tier 2, IF: 2.96)
    94.    Sim, D.S.M., Tan, C.H. (2015) Drug interactions. Chan KY, Ng PK, Sim MDS, eds. Pharmacological Basis of Acute Care. Cham: Springer International Publishing, 81-86. (Book chapter)
    95.    Leong, P.K., Fung, S.Y., Tan, C.H., Sim, S.M., Tan, N.H. (2015) Immunological cross-reactivity and neutralization of the principal toxins of Naja sumatrana and related cobra venoms by a Thai polyvalent antivenom (Neuro Polyvalent Snake Antivenom). Acta Trop 149: 86-93. (SCIE, IF: 3.222, Tier 1)
    96.    Lai, P.S., Sim, S.M., Chua, S.S., Tan, C.H., Ng, C.J., Achike, F.I., Teng, C.L. (2015) Development and validation of an instrument to assess the prescribing readiness of medical students in Malaysia. BMC Med Educ 15: 153. (SCI, IF: 2.37, Tier 2)
    97.    Tan, C.H.*, Sim, S.M., Gnanathasan, C.A., Fung, S.Y., Tan, N.H. (2014) Pharmacokinetics of the Sri Lankan hump-nosed pit viper (Hypnale hypnale) venom following intravenous and intramuscular injections of the venom into rabbits. Toxicon 79: 37-44. (SCI, IF: 3.03, Tier 3, Corresponding author*)
    98.    Yap, M.K., Tan, N.H., Sim, S.M., Fung, S.Y., Tan, C.H. (2014) Pharmacokinetics of Naja sumatrana (Equatorial spitting cobra) venom and its major toxins in experimentally envenomed rabbits. PLoS Negl Trop Dis 8, e2890. (SCIE, IF: 4.521, Tier 1)
    99.    Sim, S.M., Foong, C.C., Tan, C.H., Lai, P.S., Chua, S.S., Mohazmi, M. (2014) The use of jigsaw learning technique in teaching medical students prescribing skills. Medical Teachers 36: 182. (SCI, IF: 2.706, Tier 2,)
    100.  Leong, P.K., Tan, C.H., Sim, S.M., Fung, S.Y., Sumana, K., Sitprija, V., Tan, N.H. (2014) Cross neutralization of common Southeast Asian viperid venoms by a Thai polyvalent snake antivenom (Hemato Polyvalent Snake Antivenom). Acta Trop 132: 7-14. (SCIE, IF: 3.222)
    101.  Tan, C.H.*, Tan, N.H., Sim, S.M., Fung, S.Y., Jayalakshmi, P., Gnanathasan, C.A. (2012) Nephrotoxicity of hump-nosed pit viper (Hypnale hypnale) venom in mice is preventable by the paraspecific Hemato polyvalent antivenom (HPA). Toxicon 60: 1259-1262. (SCI, IF: 3.03, Tier 3, Corresponding author*)
    102.  Tan, C.H.*, Tan, N.H., Sim, S.M., Fung, S.Y., Gnanathasan, C.A. (2012) Immunological properties of Hypnale hypnale (hump-nosed pit viper) venom: antibody production with diagnostic and therapeutic potentials. Acta Trop 122: 267-275. (SCIE, IF: 3.222, First and corresponding author*)
    103.  Tan, C.H.*, Sim, S.M., Gnanathasan, C.A., Fung, S.Y., Ponnudurai, G., Pailoor, J., Tan, N.H. (2011) Enzymatic and toxinological activities of Hypnale hypnale (hump-nosed pit viper) venom and its fractionation by ion exchange high performance liquid chromatography. Journal of Venomous Animals and Toxins including Tropical Diseases 17: 473-485. (SCI, IF: 2.45, Tier 2, First and corresponding author*)
    104. Tan, C.H.*, Leong, P.K., Fung, S.Y., Sim, S.M., Ponnudurai, G., Ariaratnam, C., Khomvilai, S., Sitprija, V., Tan, N.H. (2011) Cross neutralization of Hypnale hypnale (hump-nosed pit viper) venom by polyvalent and monovalent Malayan pit viper antivenoms in vitro and in a rodent model. Acta Trop 117: 119-124. (SCIE, IF: 3.222, corresponding author*)

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A complete list of the publications and their links can be found at: https://scholar.google.com/citations?user=cfceeIcAAAAJ&hl=en

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